Downtown Santa Fe Vacations from $569

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $2,000 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Your Downtown Santa Fe Vacation

Book your vacation package to Downtown Santa Fe and prepare to experience its culture and loads more. Whether you're seeking adventure or relaxation, you'll find it in this much-loved neighborhood. Want to explore the sights during your trip to Downtown Santa Fe? Be sure to stop by nearby attractions like Palace of the Governors, Museum of International Folk Art and Museum of Indian Arts and Culture. Expedia can put your travel plans into action. Book your ultimate Downtown Santa Fe vacation now.

The Latest Downtown Santa Fe Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Days Inn by Wyndham Espanola

Days Inn by Wyndham Espanola

$569
per person
Dec 1 - Dec 7
found 8 hours ago
Roundtrip non-stop flight included
San Antonio (SAT) to Santa Fe (SAF)
5.8/10 (615 reviews)
Holiday Inn Express & Suites Los Alamos Entrada Park by IHG

Holiday Inn Express & Suites Los Alamos Entrada Park by IHG

$685
per person
Dec 1 - Dec 7
found 8 hours ago
Roundtrip non-stop flight included
San Antonio (SAT) to Santa Fe (SAF)
8.8/10 Excellent! (807 reviews)
Hampton Inn & Suites Los Alamos White Rock

Hampton Inn & Suites Los Alamos White Rock

$707
per person
Dec 1 - Dec 7
found 8 hours ago
Roundtrip non-stop flight included
San Antonio (SAT) to Santa Fe (SAF)
9/10 Wonderful! (734 reviews)
Room was clean, bed was comfy, breakfast was good…thank you!

Reviewed on Sep 18, 2026

Where to stay in Downtown Santa Fe

Find the best Downtown Santa Fe areas and neighborhoods for the activities you enjoy most. Learn more about Downtown Santa Fe
A cathedral interior with stained glass windows, arched ceilings, and religious statues.

Southside

1 out of top 10 points of interest in this area

Southside is known for its popular shops, and with sights like Meow Wolf and Regal Santa Fe Place, you won't get bored spending a day wandering around this part of Santa Fe.

A stone wall with a window featuring five vertical wooden beams.

Historic Eastside

1 out of top 10 points of interest in this area

While visiting Historic Eastside, you might make a stop by sights like Canyon Road and Skateboard Park.

A church with two bell towers and a large circular window.

Northeast Santa Fe

If you're looking for some top things to see and do in Northeast Santa Fe and surrounding area, you can visit New Mexico Museum of Art and Cathedral Basilica of Saint Francis of Assisi.

A winding road through a mountainous landscape with dense greenery and distant hills.

North Hills

While North Hills might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Skateboard Park and Canyon Road.

A historic church with a large circular window and two towers.

South Capitol

If you're spending some time in South Capitol, Santa Fe Children's Museum and Center for Contemporary Arts are top sights worth seeing.

Downtown Santa Fe Hotel Deals

Eldorado Hotel & Spa

Eldorado Hotel & Spa

309 W San Francisco Street Santa Fe NM
Fully refundableReserve now, pay when you stay
$267 nightly
$302 total
Oct 22 - Oct 23
Total with taxes and fees
8.8/10 Excellent! (1,520 reviews)
"Great beds, quiet, spacious rooms, and an amazing location for a completely walkable vacation."

Reviewed on Sep 23, 2026

Eldorado Hotel & Spa
La Fonda on the Plaza

La Fonda on the Plaza

100 E San Francisco St Santa Fe NM
Fully refundableReserve now, pay when you stay
$339 nightly
$390 total
Oct 18 - Oct 19
Total with taxes and fees
9.4/10 Exceptional! (1,291 reviews)
"Good food, kind staff, room cleanliness left a lot to be desired."

Reviewed on Sep 23, 2026

La Fonda on the Plaza
El Sendero Inn, an Ascend Collection Hotel

El Sendero Inn, an Ascend Collection Hotel

311 Old Santa Fe Trail Santa Fe NM
Fully refundableReserve now, pay when you stay
$159 nightly
$183 total
Oct 19 - Oct 20
Total with taxes and fees
El Sendero Inn, an Ascend Collection Hotel
See all 1,718 properties in Downtown Santa Fe
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Downtown Santa Fe attractions

A historic church with two towers, a large circular window, and a statue in front.

Santa Fe Plaza

9.4/10 (6,885 reviews)
Home to many landmarks in the heart of the city, this spacious square evokes echoes of the Spanish colonial era with its markets, bandstand and live music.
See properties
A church interior with a spiral staircase, pews, stained glass windows, and a large cross on the wall.
Photo by Daniel Nadelbach

Loretto Chapel

9.4/10 (3,147 reviews)
A mysterious spiral staircase with no known origin is the highlight of this former church that now acts as a wedding chapel and museum.
See properties
A wooden water tower labeled "Santa Fe Rail Yard" with a crowd of people and a bicycle in the foreground.
Photo by Jen - Nealys On Wheels

Santa Fe Railyard

8.8/10 (1,473 reviews)
During your visit to Santa Fe, you can do some window-shopping at Santa Fe Railyard. Experience the fascinating museums and acclaimed art scene in this romantic area.
See properties
A historic church with a clock tower, surrounded by trees and a street with cars.
Photo by Chris Corrie

Cathedral Basilica of Saint Francis of Assisi

9.4/10 (2,147 reviews)
Take a tour of this 19th-century church in the center of Santa Fe to see its statues and brightly colored stained-glass windows.
See properties
A building with the sign 'Palace of the Governors' and flags hanging overhead.

Palace of the Governors

8.8/10 (767 reviews)
You can spend time studying the exhibits at Palace of the Governors in Santa Fe. Experience the area's entertainment choices and acclaimed art scene.
See properties
A building with a distinctive architectural style, featuring a tower and a covered entrance.

New Mexico Museum of Art

9.2/10 (325 reviews)
Admire the exceptional Pueblo design of the adobe structure that houses one of the oldest art galleries in New Mexico.
See properties

Georgia O'Keefe Museum

9.2/10 (1,760 reviews)
You can spend time studying the exhibits at Georgia O'Keefe Museum during your travels in Santa Fe. Discover the area's top-notch restaurants and its fascinating museums.
See properties

New Mexico State Capitol

8.8/10 (915 reviews)
After visiting New Mexico State Capitol, make a plan to see the other sights and activities in Santa Fe. Experience the area's fascinating museums and acclaimed art scene.
See properties

Things to do

Santa Fe: Meow Wolf's House of Eternal Return Ticket

Santa Fe: Meow Wolf The House of Eternal Return Ticket

$32
per child
100% of travellers recommend
Santa Fe: Meow Wolf The House of Eternal Return Ticket
Hot Air Balloon Rides in Santa Fe

Hot Air Balloon Rides in Santa Fe

$315
per adult
100% of travellers recommend
Hot Air Balloon Rides in Santa Fe
Santa Fe Revisited

Santa Fe Revisited

$80
per adult
92% of travellers recommend
Santa Fe Revisited
See all activities in Santa Fe

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.